Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 526.9 BDBM308539

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308539 (2-chloro-N-{trans-1-[(1,5-dimethyl-1H-pyrazol-4-yl...) Show SMILES Cc1c(cnn1C)S(=O)(=O)N1C[C@@H](NC(=O)c2cccc(c2Cl)C(F)(F)F)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C23H22ClF3N4O3S/c1-14-20(11-28-30(14)2)35(33,34)31-12-17(15-7-4-3-5-8-15)19(13-31)29-22(32)16-9-6-10-18(21(16)24)23(25,26)27/h3-11,17,19H,12-13H2,1-2H3,(H,29,32)/t17-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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