Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 277.3 BDBM50004235

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Fibroblast growth factor receptor 3				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50004235 ((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...) Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12 Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR-8113 Curated by ChEMBL					Assay Description Inhibitory activity against Platelet-derived growth factor receptor alpha				J Med Chem 48: 6194-201 (2005) Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR
					More data for this Ligand-Target Pair