Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50057239
(2-Hydroxy-5-methyl-3-{(E)-3-[3-((E)-2-quinolin-2-y...)Show SMILES Cc1cc(C(O)=O)c(O)c(c1)C(=O)\C=C\c1cccc(\C=C\c2ccc3ccccc3n2)c1 Show InChI InChI=1S/C28H21NO4/c1-18-15-23(27(31)24(16-18)28(32)33)26(30)14-10-20-6-4-5-19(17-20)9-12-22-13-11-21-7-2-3-8-25(21)29-22/h2-17,31H,1H3,(H,32,33)/b12-9+,14-10+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50057239
(2-Hydroxy-5-methyl-3-{(E)-3-[3-((E)-2-quinolin-2-y...)Show SMILES Cc1cc(C(O)=O)c(O)c(c1)C(=O)\C=C\c1cccc(\C=C\c2ccc3ccccc3n2)c1 Show InChI InChI=1S/C28H21NO4/c1-18-15-23(27(31)24(16-18)28(32)33)26(30)14-10-20-6-4-5-19(17-20)9-12-22-13-11-21-7-2-3-8-25(21)29-22/h2-17,31H,1H3,(H,32,33)/b12-9+,14-10+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit
Curated by ChEMBL
| Assay Description
Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes |
J Med Chem 40: 1075-89 (1997)
Article DOI: 10.1021/jm960628d
BindingDB Entry DOI: 10.7270/Q25141XJ |
More data for this
Ligand-Target Pair | |