Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 413.4 BDBM50125904

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50125904 (CHEMBL3623878) Show SMILES Cc1cc(ccn1)-c1cccc(SCC(=O)Nc2ccc(cn2)-c2cnccn2)c1 Show InChI InChI=1S/C23H19N5OS/c1-16-11-18(7-8-25-16)17-3-2-4-20(12-17)30-15-23(29)28-22-6-5-19(13-27-22)21-14-24-9-10-26-21/h2-14H,15H2,1H3,(H,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...				Bioorg Med Chem 23: 6855-68 (2015) Article DOI: 10.1016/j.bmc.2015.09.048 BindingDB Entry DOI: 10.7270/Q2J10500
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