Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human)) | BDBM201296
(US9187424, 60)Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccccc2Cl)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |c:8| Show InChI InChI=1S/C30H25ClF6N2O3/c1-18-7-9-19(10-8-18)22-17-28(30(35,36)37,20-11-13-21(14-12-20)42-16-4-15-29(32,33)34)39-27(41)25(22)26(40)38-24-6-3-2-5-23(24)31/h2-3,5-14H,4,15-17H2,1H3,(H,38,40)(H,39,41) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff... |
US Patent US9187424 (2015)
BindingDB Entry DOI: 10.7270/Q2FQ9VFG |
More data for this
Ligand-Target Pair | |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human)) | BDBM201296
(US9187424, 60)Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccccc2Cl)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |c:8| Show InChI InChI=1S/C30H25ClF6N2O3/c1-18-7-9-19(10-8-18)22-17-28(30(35,36)37,20-11-13-21(14-12-20)42-16-4-15-29(32,33)34)39-27(41)25(22)26(40)38-24-6-3-2-5-23(24)31/h2-3,5-14H,4,15-17H2,1H3,(H,38,40)(H,39,41) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 441 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy... |
US Patent US9187424 (2015)
BindingDB Entry DOI: 10.7270/Q2FQ9VFG |
More data for this
Ligand-Target Pair | |