Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 5
(Rat 6B) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against rat neuropeptide Y5 receptor |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against human neuropeptide Y5 receptor measured as Ca+ response |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against rat neuropeptide Y1 receptor |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against rat neuropeptide Y2 receptor |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50145232
(CHEMBL311229 | {4-[(9-Methyl-4,5-dihydro-6-oxa-3-t...)Show SMILES Cc1ccc2OCCc3sc(NCC4CCN(CC4)C(=O)[C@H]4CCCO4)nc3-c2c1 Show InChI InChI=1S/C23H29N3O3S/c1-15-4-5-18-17(13-15)21-20(8-12-29-18)30-23(25-21)24-14-16-6-9-26(10-7-16)22(27)19-3-2-11-28-19/h4-5,13,16,19H,2-3,6-12,14H2,1H3,(H,24,25)/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound against rat neuropeptide Y4 receptor |
Bioorg Med Chem Lett 14: 2451-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.014 BindingDB Entry DOI: 10.7270/Q2WM1CV1 |
More data for this Ligand-Target Pair | |