Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polymerase acidic protein
(Hepatitis C virus) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Binding affinity to PA N-terminal domain (Competitive) |
ACS Chem Biol 7: 526-34 (2012)
Article DOI: 10.1021/cb200439z BindingDB Entry DOI: 10.7270/Q2JQ121G |
More data for this Ligand-Target Pair | |
Malate synthase G [C619A]
(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB D3R
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R
| Assay Description DNTB-Coupled_Enzyme_Assay |
D3R 223: (2015)
BindingDB Entry DOI: 10.7270/Q2NC602G |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
(Hepatitis C virus) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Plaque growth inhibition |
ACS Chem Biol 7: 526-34 (2012)
Article DOI: 10.1021/cb200439z BindingDB Entry DOI: 10.7270/Q2JQ121G |
More data for this Ligand-Target Pair | |