Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251734
(US10100018, Example 70 | US9464060, 70)Show SMILES Cc1ccccc1Oc1ccc(cc1)C(=O)N(Cc1ccc(cc1)C(O)=O)CC(F)(F)F Show InChI InChI=1S/C24H20F3NO4/c1-16-4-2-3-5-21(16)32-20-12-10-18(11-13-20)22(29)28(15-24(25,26)27)14-17-6-8-19(9-7-17)23(30)31/h2-13H,14-15H2,1H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251734
(US10100018, Example 70 | US9464060, 70)Show SMILES Cc1ccccc1Oc1ccc(cc1)C(=O)N(Cc1ccc(cc1)C(O)=O)CC(F)(F)F Show InChI InChI=1S/C24H20F3NO4/c1-16-4-2-3-5-21(16)32-20-12-10-18(11-13-20)22(29)28(15-24(25,26)27)14-17-6-8-19(9-7-17)23(30)31/h2-13H,14-15H2,1H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251734
(US10100018, Example 70 | US9464060, 70)Show SMILES Cc1ccccc1Oc1ccc(cc1)C(=O)N(Cc1ccc(cc1)C(O)=O)CC(F)(F)F Show InChI InChI=1S/C24H20F3NO4/c1-16-4-2-3-5-21(16)32-20-12-10-18(11-13-20)22(29)28(15-24(25,26)27)14-17-6-8-19(9-7-17)23(30)31/h2-13H,14-15H2,1H3,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM251734
(US10100018, Example 70 | US9464060, 70)Show SMILES Cc1ccccc1Oc1ccc(cc1)C(=O)N(Cc1ccc(cc1)C(O)=O)CC(F)(F)F Show InChI InChI=1S/C24H20F3NO4/c1-16-4-2-3-5-21(16)32-20-12-10-18(11-13-20)22(29)28(15-24(25,26)27)14-17-6-8-19(9-7-17)23(30)31/h2-13H,14-15H2,1H3,(H,30,31) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |