Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454591
(US10717746, Example 76)Show SMILES Cc1cnc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)C2COC2)cc1-c1cnn2CC(C)(C)Cc12 |r| Show InChI InChI=1S/C25H33N5O3/c1-15-10-26-22(8-19(15)20-11-27-30-14-25(2,3)9-21(20)30)29-23(31)16-5-4-6-18(7-16)28-24(32)17-12-33-13-17/h8,10-11,16-18H,4-7,9,12-14H2,1-3H3,(H,28,32)(H,26,29,31)/t16-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description
Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454591
(US10717746, Example 76)Show SMILES Cc1cnc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)C2COC2)cc1-c1cnn2CC(C)(C)Cc12 |r| Show InChI InChI=1S/C25H33N5O3/c1-15-10-26-22(8-19(15)20-11-27-30-14-25(2,3)9-21(20)30)29-23(31)16-5-4-6-18(7-16)28-24(32)17-12-33-13-17/h8,10-11,16-18H,4-7,9,12-14H2,1-3H3,(H,28,32)(H,26,29,31)/t16-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description
Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this
Ligand-Target Pair | |