Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 613.6 BDBM435342

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435342 ((trans)-N-((2-(2-(4,4-dimethyloxazolidin- 3-yl)-2-...) Show SMILES Cc1noc(n1)[C@@H]1CC1C(=O)NCc1ccc(-c2cccc(OC(F)(F)F)c2)c2CCN(CC(=O)N3COCC3(C)C)Cc12 |r| Show InChI InChI=1S/C31H34F3N5O5/c1-18-36-29(44-37-18)25-12-24(25)28(41)35-13-20-7-8-22(19-5-4-6-21(11-19)43-31(32,33)34)23-9-10-38(14-26(20)23)15-27(40)39-17-42-16-30(39,2)3/h4-8,11,24-25H,9-10,12-17H2,1-3H3,(H,35,41)/t24?,25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
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