Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50151507
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCN(CC2)C2CCCCC2Cn2cncn2)cc1 Show InChI InChI=1S/C32H40ClN7O2/c33-27-11-9-23(10-12-27)17-29(37-31(41)28-18-24-5-1-2-6-25(24)19-35-28)32(42)39-15-13-38(14-16-39)30-8-4-3-7-26(30)20-40-22-34-21-36-40/h1-2,5-6,9-12,21-22,26,28-30,35H,3-4,7-8,13-20H2,(H,37,41)/t26?,28?,29-,30?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity towards Melanocortin 4 receptor using [125I]NDP-MSH |
J Med Chem 47: 4613-26 (2004)
Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ |
More data for this Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50151507
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCN(CC2)C2CCCCC2Cn2cncn2)cc1 Show InChI InChI=1S/C32H40ClN7O2/c33-27-11-9-23(10-12-27)17-29(37-31(41)28-18-24-5-1-2-6-25(24)19-35-28)32(42)39-15-13-38(14-16-39)30-8-4-3-7-26(30)20-40-22-34-21-36-40/h1-2,5-6,9-12,21-22,26,28-30,35H,3-4,7-8,13-20H2,(H,37,41)/t26?,28?,29-,30?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity towards Melanocortin 1 receptor using [125I]NDP-MSH |
J Med Chem 47: 4613-26 (2004)
Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ |
More data for this Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50151507
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCN(CC2)C2CCCCC2Cn2cncn2)cc1 Show InChI InChI=1S/C32H40ClN7O2/c33-27-11-9-23(10-12-27)17-29(37-31(41)28-18-24-5-1-2-6-25(24)19-35-28)32(42)39-15-13-38(14-16-39)30-8-4-3-7-26(30)20-40-22-34-21-36-40/h1-2,5-6,9-12,21-22,26,28-30,35H,3-4,7-8,13-20H2,(H,37,41)/t26?,28?,29-,30?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity towards Melanocortin 3 receptor using [125I]NDP-MSH |
J Med Chem 47: 4613-26 (2004)
Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ |
More data for this Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50151507
(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)Show SMILES Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCN(CC2)C2CCCCC2Cn2cncn2)cc1 Show InChI InChI=1S/C32H40ClN7O2/c33-27-11-9-23(10-12-27)17-29(37-31(41)28-18-24-5-1-2-6-25(24)19-35-28)32(42)39-15-13-38(14-16-39)30-8-4-3-7-26(30)20-40-22-34-21-36-40/h1-2,5-6,9-12,21-22,26,28-30,35H,3-4,7-8,13-20H2,(H,37,41)/t26?,28?,29-,30?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity towards Melanocortin 5 receptor using [125I]NDP-MSH |
J Med Chem 47: 4613-26 (2004)
Article DOI: 10.1021/jm0311285 BindingDB Entry DOI: 10.7270/Q2BR8RNZ |
More data for this Ligand-Target Pair | |