Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50060724
(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC2CCNCC2)cc1 Show InChI InChI=1S/C34H45ClN4O2/c35-27-8-10-29(11-9-27)41-25-32-34(33(40)24-37-21-15-28(16-22-37)38-19-4-1-5-20-38)30-6-2-3-7-31(30)39(32)23-14-26-12-17-36-18-13-26/h2-3,6-11,26,28,36H,1,4-5,12-25H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for Neuropeptide Y receptor type 1 expressed in AV-12 cells |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50060724
(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC2CCNCC2)cc1 Show InChI InChI=1S/C34H45ClN4O2/c35-27-8-10-29(11-9-27)41-25-32-34(33(40)24-37-21-15-28(16-22-37)38-19-4-1-5-20-38)30-6-2-3-7-31(30)39(32)23-14-26-12-17-36-18-13-26/h2-3,6-11,26,28,36H,1,4-5,12-25H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 4 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50060724
(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC2CCNCC2)cc1 Show InChI InChI=1S/C34H45ClN4O2/c35-27-8-10-29(11-9-27)41-25-32-34(33(40)24-37-21-15-28(16-22-37)38-19-4-1-5-20-38)30-6-2-3-7-31(30)39(32)23-14-26-12-17-36-18-13-26/h2-3,6-11,26,28,36H,1,4-5,12-25H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 5 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50060724
(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)Show SMILES Clc1ccc(OCc2c(C(=O)CN3CCC(CC3)N3CCCCC3)c3ccccc3n2CCC2CCNCC2)cc1 Show InChI InChI=1S/C34H45ClN4O2/c35-27-8-10-29(11-9-27)41-25-32-34(33(40)24-37-21-15-28(16-22-37)38-19-4-1-5-20-38)30-6-2-3-7-31(30)39(32)23-14-26-12-17-36-18-13-26/h2-3,6-11,26,28,36H,1,4-5,12-25H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Affinity for human Neuropeptide Y receptor type 2 |
J Med Chem 40: 3712-4 (1997)
Article DOI: 10.1021/jm970512x BindingDB Entry DOI: 10.7270/Q2HQ3Z1P |
More data for this Ligand-Target Pair | |