Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 346.8 BDBM50024914

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50024914 (6-Chloro-3-(6-imidazol-1-yl-hexyl)-1H-quinazoline-...) Show SMILES Clc1ccc2[nH]c(=O)n(CCCCCCn3ccnc3)c(=O)c2c1 Show InChI InChI=1S/C17H19ClN4O2/c18-13-5-6-15-14(11-13)16(23)22(17(24)20-15)9-4-2-1-3-8-21-10-7-19-12-21/h5-7,10-12H,1-4,8-9H2,(H,20,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Tested for inhibition of thromboxane synthetase from spontaneously hypertensive rats				J Med Chem 30: 2277-83 (1988) BindingDB Entry DOI: 10.7270/Q23T9HT6
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