Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 334.7 BDBM50105559

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Clc1cccc(c1)-c1ccc2n(Cc3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C20H15ClN2O/c21-17-8-4-7-15(11-17)16-9-10-19-18(12-16)22-20(24)23(19)13-14-5-2-1-3-6-14/h1-12H,13H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Clc1cccc(c1)-c1ccc2n(Cc3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C20H15ClN2O/c21-17-8-4-7-15(11-17)16-9-10-19-18(12-16)22-20(24)23(19)13-14-5-2-1-3-6-14/h1-12H,13H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cells				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Clc1cccc(c1)-c1ccc2n(Cc3ccccc3)c(=O)[nH]c2c1 Show InChI InChI=1S/C20H15ClN2O/c21-17-8-4-7-15(11-17)16-9-10-19-18(12-16)22-20(24)23(19)13-14-5-2-1-3-6-14/h1-12H,13H2,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
					More data for this Ligand-Target Pair