Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM12792
(5-amidinoindole 26 | N-[4-(1H-1,3-benzodiazol-1-yl...)Show SMILES Cn1cc(C(Cc2ccccc2)C(=O)Nc2ccc(cc2F)-n2cnc3ccccc23)c2cc(ccc12)C(N)=N Show InChI InChI=1S/C32H27FN6O/c1-38-18-25(23-16-21(31(34)35)11-14-29(23)38)24(15-20-7-3-2-4-8-20)32(40)37-27-13-12-22(17-26(27)33)39-19-36-28-9-5-6-10-30(28)39/h2-14,16-19,24H,15H2,1H3,(H3,34,35)(H,37,40) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 160 | -38.4 | n/a | n/a | n/a | n/a | n/a | 7.0 | 22 |
Bristol-Myers Squibb Company
| Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter... |
Bioorg Med Chem Lett 14: 5269-73 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.037 BindingDB Entry DOI: 10.7270/Q2PR7T6P |
More data for this Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM12792
(5-amidinoindole 26 | N-[4-(1H-1,3-benzodiazol-1-yl...)Show SMILES Cn1cc(C(Cc2ccccc2)C(=O)Nc2ccc(cc2F)-n2cnc3ccccc23)c2cc(ccc12)C(N)=N Show InChI InChI=1S/C32H27FN6O/c1-38-18-25(23-16-21(31(34)35)11-14-29(23)38)24(15-20-7-3-2-4-8-20)32(40)37-27-13-12-22(17-26(27)33)39-19-36-28-9-5-6-10-30(28)39/h2-14,16-19,24H,15H2,1H3,(H3,34,35)(H,37,40) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
| Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter... |
Bioorg Med Chem Lett 14: 5269-73 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.037 BindingDB Entry DOI: 10.7270/Q2PR7T6P |
More data for this Ligand-Target Pair | |