Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 411.3 BDBM532280

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM532280 (4-[2-[(1-Methylimidazol-4-yl)amino]-4-pyridyl]-6-[...) Show SMILES Cn1cnc(Nc2cc(ccn2)-c2cc([nH]c(=O)c2)-c2ccccc2C(F)(F)F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM532280 (4-[2-[(1-Methylimidazol-4-yl)amino]-4-pyridyl]-6-[...) Show SMILES Cn1cnc(Nc2cc(ccn2)-c2cc([nH]c(=O)c2)-c2ccccc2C(F)(F)F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...				Citation and Details BindingDB Entry DOI: 10.7270/Q28055SC
					More data for this Ligand-Target Pair