Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 441.9 BDBM308594

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308594 (3-chloro-5-({trans-1-[(1-methyl-1H-imidazol-4-yl)s...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2cc(Cl)cc(c2)C#N)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C21H20ClN5O2S/c1-26-13-21(24-14-26)30(28,29)27-11-19(16-5-3-2-4-6-16)20(12-27)25-18-8-15(10-23)7-17(22)9-18/h2-9,13-14,19-20,25H,11-12H2,1H3/t19-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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