Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 508.9 BDBM309270

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309270 (Trans-N-[4-chloro-3-(trifluoromethoxy)phenyl]-1-[(...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@@H](Nc2ccc(Cl)c(OC(F)(F)F)c2)[C@@H](C1)[C@@H]1CCCOC1 Show InChI InChI=1S/C20H24ClF3N4O4S/c1-27-10-19(25-12-27)33(29,30)28-8-15(13-3-2-6-31-11-13)17(9-28)26-14-4-5-16(21)18(7-14)32-20(22,23)24/h4-5,7,10,12-13,15,17,26H,2-3,6,8-9,11H2,1H3/t13-,15+,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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