Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 496.4 BDBM308729

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308729 (Trans-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H]([C@@H](C1)c1ccc(F)cc1)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H20F4N4O3S/c1-29-12-20(27-13-29)34(32,33)30-10-18(14-2-6-16(23)7-3-14)19(11-30)21(31)28-17-8-4-15(5-9-17)22(24,25)26/h2-9,12-13,18-19H,10-11H2,1H3,(H,28,31)/t18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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