Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM255176
(US9475817, 135)Show SMILES Cn1nc(c(c1N1CCN(CCC(F)(F)F)CC1)-c1ccc2nc(NC(=O)c3ccnc(c3)N3CCOCC3)cn2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H34F4N10O2/c1-43-32(46-14-12-44(13-15-46)11-9-33(35,36)37)29(30(42-43)22-2-4-24(34)5-3-22)25-6-7-27-39-26(21-47(27)41-25)40-31(48)23-8-10-38-28(20-23)45-16-18-49-19-17-45/h2-8,10,20-21H,9,11-19H2,1H3,(H,40,48) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM255176
(US9475817, 135)Show SMILES Cn1nc(c(c1N1CCN(CCC(F)(F)F)CC1)-c1ccc2nc(NC(=O)c3ccnc(c3)N3CCOCC3)cn2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H34F4N10O2/c1-43-32(46-14-12-44(13-15-46)11-9-33(35,36)37)29(30(42-43)22-2-4-24(34)5-3-22)25-6-7-27-39-26(21-47(27)41-25)40-31(48)23-8-10-38-28(20-23)45-16-18-49-19-17-45/h2-8,10,20-21H,9,11-19H2,1H3,(H,40,48) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |