Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 450.3 BDBM50239442

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Anoctamin-1 (Homo sapiens (Human))	BDBM50239442 (CHEMBL3134587) Show SMILES FC(F)(F)C(=O)Nc1sc2CCCCCc2c1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H16F6N2O2S/c20-18(21,22)10-6-8-11(9-7-10)26-15(28)14-12-4-2-1-3-5-13(12)30-16(14)27-17(29)19(23,24)25/h6-9H,1-5H2,(H,26,28)(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
San Francisco State University Curated by ChEMBL					Assay Description Inhibition of human TMEM16A expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...				J Med Chem 60: 4626-4635 (2017) Article DOI: 10.1021/acs.jmedchem.7b00020 BindingDB Entry DOI: 10.7270/Q2FT8P5G
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