Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 530.9 BDBM488013

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM488013 (N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...) Show SMILES FC(F)(F)c1c(cnn1-c1cnc(C2CC2)c2sccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1 Show InChI InChI=1S/C22H14ClF3N8OS/c23-15-7-12(8-28-20(15)34-29-4-5-30-34)32-21(35)14-9-31-33(19(14)22(24,25)26)16-10-27-17(11-1-2-11)18-13(16)3-6-36-18/h3-11H,1-2H2,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
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