Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 471.4 BDBM308632

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308632 (3-{[trans-4-phenyl-1-{[4-(trifluoromethyl)phenyl]s...) Show SMILES FC(F)(F)c1ccc(cc1)S(=O)(=O)N1C[C@@H](Nc2cccc(c2)C#N)[C@@H](C1)c1ccccc1 Show InChI InChI=1S/C24H20F3N3O2S/c25-24(26,27)19-9-11-21(12-10-19)33(31,32)30-15-22(18-6-2-1-3-7-18)23(16-30)29-20-8-4-5-17(13-20)14-28/h1-13,22-23,29H,15-16H2/t22-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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