Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Rattus norvegicus (rat)) | BDBM50025023
(CHEMBL3337851)Show SMILES FC(F)Oc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H9F4N3O4/c17-14(18)25-8-3-1-2-7(4-8)13(24)23-15-21-9-5-11-12(6-10(9)22-15)27-16(19,20)26-11/h1-6,14H,(H2,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Ulm University Hospital
Curated by ChEMBL
| Assay Description
Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography |
J Med Chem 57: 7933-46 (2014)
Article DOI: 10.1021/jm500600b
BindingDB Entry DOI: 10.7270/Q2N0183J |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform delta
(Rattus norvegicus (rat)) | BDBM50025023
(CHEMBL3337851)Show SMILES FC(F)Oc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H9F4N3O4/c17-14(18)25-8-3-1-2-7(4-8)13(24)23-15-21-9-5-11-12(6-10(9)22-15)27-16(19,20)26-11/h1-6,14H,(H2,21,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Ulm University Hospital
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography |
J Med Chem 57: 7933-46 (2014)
Article DOI: 10.1021/jm500600b
BindingDB Entry DOI: 10.7270/Q2N0183J |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50025023
(CHEMBL3337851)Show SMILES FC(F)Oc1cccc(c1)C(=O)Nc1nc2cc3OC(F)(F)Oc3cc2[nH]1 Show InChI InChI=1S/C16H9F4N3O4/c17-14(18)25-8-3-1-2-7(4-8)13(24)23-15-21-9-5-11-12(6-10(9)22-15)27-16(19,20)26-11/h1-6,14H,(H2,21,22,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Ulm University Hospital
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography |
J Med Chem 57: 7933-46 (2014)
Article DOI: 10.1021/jm500600b
BindingDB Entry DOI: 10.7270/Q2N0183J |
More data for this
Ligand-Target Pair | |