Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150569
(US10238633, Example 243 | US8987249, 243 | US97136...)Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1cnn(c1)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN5O3S/c26-23-12-16(19-14-28-31(15-19)35(33,34)22-4-2-1-3-5-22)6-7-17(23)10-21(13-27)30-25(32)24-18-8-9-20(11-18)29-24/h1-7,12,14-15,18,20-21,24,29H,8-11H2,(H,30,32)/t18-,20+,21-,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys... |
US Patent US8987249 (2015)
BindingDB Entry DOI: 10.7270/Q2KP80WG |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150569
(US10238633, Example 243 | US8987249, 243 | US97136...)Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1cnn(c1)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN5O3S/c26-23-12-16(19-14-28-31(15-19)35(33,34)22-4-2-1-3-5-22)6-7-17(23)10-21(13-27)30-25(32)24-18-8-9-20(11-18)29-24/h1-7,12,14-15,18,20-21,24,29H,8-11H2,(H,30,32)/t18-,20+,21-,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation
| Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ... |
J Med Chem 50: 984-1000 (2007)
BindingDB Entry DOI: 10.7270/Q22R3TZF |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150569
(US10238633, Example 243 | US8987249, 243 | US97136...)Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1cnn(c1)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN5O3S/c26-23-12-16(19-14-28-31(15-19)35(33,34)22-4-2-1-3-5-22)6-7-17(23)10-21(13-27)30-25(32)24-18-8-9-20(11-18)29-24/h1-7,12,14-15,18,20-21,24,29H,8-11H2,(H,30,32)/t18-,20+,21-,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description
Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod.... |
US Patent US9713606 (2017)
BindingDB Entry DOI: 10.7270/Q21G0P8M |
More data for this
Ligand-Target Pair | |