Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 372.4 BDBM150531

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150531 (US10238633, Example 205 | US8987249, 205 | US97136...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)N1CCOCC1 |r| Show InChI InChI=1S/C20H25FN4O2/c21-18-11-17(25-5-7-27-8-6-25)4-2-13(18)9-16(12-22)24-20(26)19-14-1-3-15(10-14)23-19/h2,4,11,14-16,19,23H,1,3,5-10H2,(H,24,26)/t14-,15+,16-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25.9	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8987249 (2015) BindingDB Entry DOI: 10.7270/Q2KP80WG
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150531 (US10238633, Example 205 | US8987249, 205 | US97136...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)N1CCOCC1 |r| Show InChI InChI=1S/C20H25FN4O2/c21-18-11-17(25-5-7-27-8-6-25)4-2-13(18)9-16(12-22)24-20(26)19-14-1-3-15(10-14)23-19/h2,4,11,14-16,19,23H,1,3,5-10H2,(H,24,26)/t14-,15+,16-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25.9	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q22R3TZF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150531 (US10238633, Example 205 | US8987249, 205 | US97136...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)N1CCOCC1 |r| Show InChI InChI=1S/C20H25FN4O2/c21-18-11-17(25-5-7-27-8-6-25)4-2-13(18)9-16(12-22)24-20(26)19-14-1-3-15(10-14)23-19/h2,4,11,14-16,19,23H,1,3,5-10H2,(H,24,26)/t14-,15+,16-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25.9	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....				US Patent US9713606 (2017) BindingDB Entry DOI: 10.7270/Q21G0P8M
					More data for this Ligand-Target Pair