Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 434.3 BDBM372463

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372463 (N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]...) Show SMILES Fc1ccc(Cn2ncc(NC(=O)Cc3ccc(nc3)N3CCC(F)(F)C3)n2)cc1F Show InChI InChI=1S/C20H18F4N6O/c21-15-3-1-14(7-16(15)22)11-30-26-10-17(28-30)27-19(31)8-13-2-4-18(25-9-13)29-6-5-20(23,24)12-29/h1-4,7,9-10H,5-6,8,11-12H2,(H,27,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
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