Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50062510
((S)-2-((R)-1-Amino-1-carboxy-4,4-diphenyl-butyl)-c...)Show SMILES N[C@](CCC(c1ccccc1)c1ccccc1)(C1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C21H23NO4/c22-21(20(25)26,18-13-17(18)19(23)24)12-11-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-10,16-18H,11-13,22H2,(H,23,24)(H,25,26)/t17-,18?,21+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r... |
J Med Chem 41: 346-57 (1998)
Article DOI: 10.1021/jm970497w BindingDB Entry DOI: 10.7270/Q22F7MJ0 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50062510
((S)-2-((R)-1-Amino-1-carboxy-4,4-diphenyl-butyl)-c...)Show SMILES N[C@](CCC(c1ccccc1)c1ccccc1)(C1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C21H23NO4/c22-21(20(25)26,18-13-17(18)19(23)24)12-11-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-10,16-18H,11-13,22H2,(H,23,24)(H,25,26)/t17-,18?,21+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r... |
J Med Chem 41: 346-57 (1998)
Article DOI: 10.1021/jm970497w BindingDB Entry DOI: 10.7270/Q22F7MJ0 |
More data for this Ligand-Target Pair | |