Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prothrombin
(Homo sapiens (Human)) | BDBM50349334
(CHEMBL1809239)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)C(=O)OCc2ccccc2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C37H45N7O7S/c38-34(39)30-15-13-27(14-16-30)24-40-35(46)32-12-7-19-44(32)36(47)31(41-52(49,50)26-29-10-5-2-6-11-29)17-18-33(45)42-20-22-43(23-21-42)37(48)51-25-28-8-3-1-4-9-28/h1-6,8-11,13-16,31-32,41H,7,12,17-26H2,(H3,38,39)(H,40,46)/t31-,32+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Transmembrane protease serine 11D
(Homo sapiens (Human)) | BDBM50349334
(CHEMBL1809239)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)C(=O)OCc2ccccc2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C37H45N7O7S/c38-34(39)30-15-13-27(14-16-30)24-40-35(46)32-12-7-19-44(32)36(47)31(41-52(49,50)26-29-10-5-2-6-11-29)17-18-33(45)42-20-22-43(23-21-42)37(48)51-25-28-8-3-1-4-9-28/h1-6,8-11,13-16,31-32,41H,7,12,17-26H2,(H3,38,39)(H,40,46)/t31-,32+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal... |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50349334
(CHEMBL1809239)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)C(=O)OCc2ccccc2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C37H45N7O7S/c38-34(39)30-15-13-27(14-16-30)24-40-35(46)32-12-7-19-44(32)36(47)31(41-52(49,50)26-29-10-5-2-6-11-29)17-18-33(45)42-20-22-43(23-21-42)37(48)51-25-28-8-3-1-4-9-28/h1-6,8-11,13-16,31-32,41H,7,12,17-26H2,(H3,38,39)(H,40,46)/t31-,32+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of factor 10a |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50349334
(CHEMBL1809239)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)C(=O)OCc2ccccc2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C37H45N7O7S/c38-34(39)30-15-13-27(14-16-30)24-40-35(46)32-12-7-19-44(32)36(47)31(41-52(49,50)26-29-10-5-2-6-11-29)17-18-33(45)42-20-22-43(23-21-42)37(48)51-25-28-8-3-1-4-9-28/h1-6,8-11,13-16,31-32,41H,7,12,17-26H2,(H3,38,39)(H,40,46)/t31-,32+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description Inhibition of plasmin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033 BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this Ligand-Target Pair | |