Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 291.3 BDBM50027291

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine protease 1 (Bos taurus (bovine))	BDBM50027291 (1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidi...) Show SMILES NC(=N)c1cccc(Cn2ccc3cc(ccc23)C(N)=N)c1 Show InChI InChI=1S/C17H17N5/c18-16(19)13-3-1-2-11(8-13)10-22-7-6-12-9-14(17(20)21)4-5-15(12)22/h1-9H,10H2,(H3,18,19)(H3,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against bovine trypsin				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50027291 (1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidi...) Show SMILES NC(=N)c1cccc(Cn2ccc3cc(ccc23)C(N)=N)c1 Show InChI InChI=1S/C17H17N5/c18-16(19)13-3-1-2-11(8-13)10-22-7-6-12-9-14(17(20)21)4-5-15(12)22/h1-9H,10H2,(H3,18,19)(H3,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against bovine thrombin				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50027291 (1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidi...) Show SMILES NC(=N)c1cccc(Cn2ccc3cc(ccc23)C(N)=N)c1 Show InChI InChI=1S/C17H17N5/c18-16(19)13-3-1-2-11(8-13)10-22-7-6-12-9-14(17(20)21)4-5-15(12)22/h1-9H,10H2,(H3,18,19)(H3,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Urokinase				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50027291 (1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidi...) Show SMILES NC(=N)c1cccc(Cn2ccc3cc(ccc23)C(N)=N)c1 Show InChI InChI=1S/C17H17N5/c18-16(19)13-3-1-2-11(8-13)10-22-7-6-12-9-14(17(20)21)4-5-15(12)22/h1-9H,10H2,(H3,18,19)(H3,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against human plasminogen				J Med Chem 26: 294-8 (1983) BindingDB Entry DOI: 10.7270/Q2NV9H8B
					More data for this Ligand-Target Pair