| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urokinase-type plasminogen activator |
|---|
| Ligand | BDBM50027291 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_212984 |
|---|
| Ki | 36000±n/a nM |
|---|
| Citation |  Tidwell, RR; Geratz, JD; Dubovi, EJ Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin. J Med Chem26:294-8 (1983) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urokinase-type plasminogen activator |
|---|
| Name: | Urokinase-type plasminogen activator |
|---|
| Synonyms: | 3.4.21.73 | PLAU | U-plasminogen activator | UROK_HUMAN | Urokinase | Urokinase-type plasminogen activator (uPA) | Urokinase-type plasminogen activator chain B | Urokinase-type plasminogen activator long chain A | Urokinase-type plasminogen activator short chain A | Urokinase-type plasminogen activator/surface receptor | uPA |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48528.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00749 |
|---|
| Residue: | 431 |
|---|
| Sequence: | MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ
HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN
YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII
GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG
RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL
PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML
CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR
SHTKEENGLAL
|
|
|
|---|
| BDBM50027291 |
|---|
| n/a |
|---|
| Name | BDBM50027291 |
|---|
| Synonyms: | 1-(3-Carbamimidoyl-benzyl)-1H-indole-5-carboxamidine | CHEMBL101726 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17N5 |
|---|
| Mol. Mass. | 291.3504 |
|---|
| SMILES | NC(=N)c1cccc(Cn2ccc3cc(ccc23)C(N)=N)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
