Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kinesin-like protein KIF11
(Homo sapiens (Human)) | BDBM50293747
(1-(pyridin-2-ylmethyl)-2-(4-sulfamoylphenylamino)-...)Show SMILES NC(=O)c1ccc2n(Cc3ccccn3)c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1 Show InChI InChI=1S/C20H18N6O3S/c21-19(27)13-4-9-18-17(11-13)25-20(26(18)12-15-3-1-2-10-23-15)24-14-5-7-16(8-6-14)30(22,28)29/h1-11H,12H2,(H2,21,27)(H,24,25)(H2,22,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human kinesin spindle protein by endpoint assay |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |
Kinesin heavy chain isoform 5A
(Homo sapiens (Human)) | BDBM50293747
(1-(pyridin-2-ylmethyl)-2-(4-sulfamoylphenylamino)-...)Show SMILES NC(=O)c1ccc2n(Cc3ccccn3)c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1 Show InChI InChI=1S/C20H18N6O3S/c21-19(27)13-4-9-18-17(11-13)25-20(26(18)12-15-3-1-2-10-23-15)24-14-5-7-16(8-6-14)30(22,28)29/h1-11H,12H2,(H2,21,27)(H,24,25)(H2,22,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of nKHC |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |
Kinesin-like protein KIF3B
(Homo sapiens (Human)) | BDBM50293747
(1-(pyridin-2-ylmethyl)-2-(4-sulfamoylphenylamino)-...)Show SMILES NC(=O)c1ccc2n(Cc3ccccn3)c(Nc3ccc(cc3)S(N)(=O)=O)nc2c1 Show InChI InChI=1S/C20H18N6O3S/c21-19(27)13-4-9-18-17(11-13)25-20(26(18)12-15-3-1-2-10-23-15)24-14-5-7-16(8-6-14)30(22,28)29/h1-11H,12H2,(H2,21,27)(H,24,25)(H2,22,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Kif3B |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |