Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 334.3 BDBM50326560

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein phosphatase alpha (Homo sapiens (Human))	BDBM50326560 (2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...) Show SMILES NC(Cc1ccc2oc3cc(=O)c4ccccc4c3nc2c1)C(O)=O Show InChI InChI=1S/C19H14N2O4/c20-13(19(23)24)7-10-5-6-16-14(8-10)21-18-12-4-2-1-3-11(12)15(22)9-17(18)25-16/h1-6,8-9,13H,7,20H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 7				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase beta (Homo sapiens (Human))	BDBM50326560 (2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...) Show SMILES NC(Cc1ccc2oc3cc(=O)c4ccccc4c3nc2c1)C(O)=O Show InChI InChI=1S/C19H14N2O4/c20-13(19(23)24)7-10-5-6-16-14(8-10)21-18-12-4-2-1-3-11(12)15(22)9-17(18)25-16/h1-6,8-9,13H,7,20H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	5.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase B assessed as change in enzyme activity at pH 5				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase alpha (Homo sapiens (Human))	BDBM50326560 (2-amino-3-(5-oxo-5H-benzo[a]phenoxazin-10-yl)propa...) Show SMILES NC(Cc1ccc2oc3cc(=O)c4ccccc4c3nc2c1)C(O)=O Show InChI InChI=1S/C19H14N2O4/c20-13(19(23)24)7-10-5-6-16-14(8-10)21-18-12-4-2-1-3-11(12)15(22)9-17(18)25-16/h1-6,8-9,13H,7,20H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	5.0	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic protein tyrosine phosphatase A assessed as change in enzyme activity at pH 5				Bioorg Med Chem 18: 5449-56 (2010) Article DOI: 10.1016/j.bmc.2010.04.050 BindingDB Entry DOI: 10.7270/Q2Q52QMC
					More data for this Ligand-Target Pair