Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bifunctional epoxide hydrolase 2
(Homo sapiens (Human)) | BDBM50541953
(CHEMBL4644372)Show SMILES O=C(CCc1ccc(OCc2ccccc2)cc1)NCC1CCN(Cc2cccs2)CC1 Show InChI InChI=1S/C27H32N2O2S/c30-27(28-19-23-14-16-29(17-15-23)20-26-7-4-18-32-26)13-10-22-8-11-25(12-9-22)31-21-24-5-2-1-3-6-24/h1-9,11-12,18,23H,10,13-17,19-21H2,(H,28,30) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full length sEH (1 to 555 residues) expressed in Escherichia coli BL21 DE3 cells assessed as reduction in 6-methoxyna... |
ACS Med Chem Lett 11: 1244-1249 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00102
BindingDB Entry DOI: 10.7270/Q2FB56H6 |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50541953
(CHEMBL4644372)Show SMILES O=C(CCc1ccc(OCc2ccccc2)cc1)NCC1CCN(Cc2cccs2)CC1 Show InChI InChI=1S/C27H32N2O2S/c30-27(28-19-23-14-16-29(17-15-23)20-26-7-4-18-32-26)13-10-22-8-11-25(12-9-22)31-21-24-5-2-1-3-6-24/h1-9,11-12,18,23H,10,13-17,19-21H2,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-... |
ACS Med Chem Lett 11: 1244-1249 (2020)
Article DOI: 10.1021/acsmedchemlett.0c00102
BindingDB Entry DOI: 10.7270/Q2FB56H6 |
More data for this
Ligand-Target Pair | |