Found 5 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50073048
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1 Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in rat |
J Med Chem 42: 181-201 (1999)
Article DOI: 10.1021/jm980521l
BindingDB Entry DOI: 10.7270/Q2T43S8P |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50073048
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1 Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34) | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against human Neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligand |
Bioorg Med Chem Lett 11: 2283-6 (2001)
BindingDB Entry DOI: 10.7270/Q2NZ86WB |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(RAT) | BDBM50073048
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1 Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34) | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
The compound was tested for the binding affinity against Neuropeptide Y receptor type 4 |
J Med Chem 42: 181-201 (1999)
Article DOI: 10.1021/jm980521l
BindingDB Entry DOI: 10.7270/Q2T43S8P |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(RAT) | BDBM50073048
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1 Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34) | PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
The compound was tested for the binding affinity against Neuropeptide Y receptor type 2 |
J Med Chem 42: 181-201 (1999)
Article DOI: 10.1021/jm980521l
BindingDB Entry DOI: 10.7270/Q2T43S8P |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(RAT) | BDBM50073048
(2-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)Show SMILES O=C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)Nc1ccc2C(=O)c3ccccc3-c2c1 Show InChI InChI=1S/C27H24N4O3/c32-25(28-17-9-10-21-22(15-17)19-5-1-2-6-20(19)26(21)33)16-30-13-11-18(12-14-30)31-24-8-4-3-7-23(24)29-27(31)34/h1-10,15,18H,11-14,16H2,(H,28,32)(H,29,34) | PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
The compound was tested for the binding affinity against NPY1 (Neuropeptide Y receptor type 1) |
J Med Chem 42: 181-201 (1999)
Article DOI: 10.1021/jm980521l
BindingDB Entry DOI: 10.7270/Q2T43S8P |
More data for this
Ligand-Target Pair | |