Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 574.6 BDBM50074565

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (GUINEA PIG)	BDBM50074565 (2-{2-[4-(3-{1-[2-(1,3-dioxo-2,3-dihydro-1H-2-isoin...) Show SMILES O=C1N(CCC[n+]2ccc(CCCc3cc[n+](CCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12 Show InChI InChI=1S/C35H34N4O4/c40-32-28-10-1-2-11-29(28)33(41)38(32)20-6-18-36-22-14-26(15-23-36)8-5-9-27-16-24-37(25-17-27)19-7-21-39-34(42)30-12-3-4-13-31(30)35(39)43/h1-4,10-17,22-25H,5-9,18-21H2/q+2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.87E+3	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2				J Med Chem 42: 849-58 (1999) Article DOI: 10.1021/jm981023f BindingDB Entry DOI: 10.7270/Q22806RB
					More data for this Ligand-Target Pair