Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50374123
(CHEMBL273044)Show SMILES O=C1NC(Cc2ccccc2)C(=O)N(Cc2ccccc2-c2ccccc2)c2ccccc12 |w:3.3| Show InChI InChI=1S/C29H24N2O2/c32-28-25-17-9-10-18-27(25)31(29(33)26(30-28)19-21-11-3-1-4-12-21)20-23-15-7-8-16-24(23)22-13-5-2-6-14-22/h1-18,26H,19-20H2,(H,30,32) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description Agonist activity at mouse MC1R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay |
J Med Chem 51: 1423-31 (2008)
Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61 |
More data for this Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50374123
(CHEMBL273044)Show SMILES O=C1NC(Cc2ccccc2)C(=O)N(Cc2ccccc2-c2ccccc2)c2ccccc12 |w:3.3| Show InChI InChI=1S/C29H24N2O2/c32-28-25-17-9-10-18-27(25)31(29(33)26(30-28)19-21-11-3-1-4-12-21)20-23-15-7-8-16-24(23)22-13-5-2-6-14-22/h1-18,26H,19-20H2,(H,30,32) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.16E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay |
J Med Chem 51: 1423-31 (2008)
Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61 |
More data for this Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50374123
(CHEMBL273044)Show SMILES O=C1NC(Cc2ccccc2)C(=O)N(Cc2ccccc2-c2ccccc2)c2ccccc12 |w:3.3| Show InChI InChI=1S/C29H24N2O2/c32-28-25-17-9-10-18-27(25)31(29(33)26(30-28)19-21-11-3-1-4-12-21)20-23-15-7-8-16-24(23)22-13-5-2-6-14-22/h1-18,26H,19-20H2,(H,30,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description Agonist activity at mouse MC4R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay |
J Med Chem 51: 1423-31 (2008)
Article DOI: 10.1021/jm701303z BindingDB Entry DOI: 10.7270/Q2KH0P61 |
More data for this Ligand-Target Pair | |