Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 392.4 BDBM346235

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM346235 (US10202373, Compound I-49 | US10202373, Example 14) Show SMILES O=S(=O)(C1CC1)n1ccc2c(cncc12)-c1ccnc(Nc2ccncn2)c1 Show InChI InChI=1S/C19H16N6O2S/c26-28(27,14-1-2-14)25-8-5-15-16(10-21-11-17(15)25)13-3-7-22-19(9-13)24-18-4-6-20-12-23-18/h3-12,14H,1-2H2,(H,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
MILLENNIUM PHARMACEUTICALS, INC. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US10202373 (2019) BindingDB Entry DOI: 10.7270/Q2FN18BC
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