Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Renin
(Homo sapiens (Human)) | BDBM50077707
((3R,4S,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5-(n...)Show SMILES O[C@H]1CNC[C@H](OCc2ccc3ccccc3c2)[C@H]1c1ccc(OCCCOCc2ccccc2)cc1 Show InChI InChI=1S/C32H35NO4/c34-30-20-33-21-31(37-23-25-11-12-26-9-4-5-10-28(26)19-25)32(30)27-13-15-29(16-14-27)36-18-6-17-35-22-24-7-2-1-3-8-24/h1-5,7-16,19,30-34H,6,17-18,20-23H2/t30-,31-,32-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against purified recombinant human renin |
Bioorg Med Chem Lett 9: 1403-8 (1999)
BindingDB Entry DOI: 10.7270/Q20P0Z6S |
More data for this Ligand-Target Pair | |
Renin
(Homo sapiens (Human)) | BDBM50077707
((3R,4S,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5-(n...)Show SMILES O[C@H]1CNC[C@H](OCc2ccc3ccccc3c2)[C@H]1c1ccc(OCCCOCc2ccccc2)cc1 Show InChI InChI=1S/C32H35NO4/c34-30-20-33-21-31(37-23-25-11-12-26-9-4-5-10-28(26)19-25)32(30)27-13-15-29(16-14-27)36-18-6-17-35-22-24-7-2-1-3-8-24/h1-5,7-16,19,30-34H,6,17-18,20-23H2/t30-,31-,32-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd.
Curated by ChEMBL
| Assay Description Inhibitory activity against purified recombinant human renin |
Bioorg Med Chem Lett 9: 1403-8 (1999)
BindingDB Entry DOI: 10.7270/Q20P0Z6S |
More data for this Ligand-Target Pair | |