Found 7 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-lactamase TEM
(Escherichia coli) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article
| 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli |
Bioorg Med Chem Lett 4: 1229-1234 (1994)
Article DOI: 10.1016/S0960-894X(01)80336-X BindingDB Entry DOI: 10.7270/Q2W9595N |
More data for this Ligand-Target Pair | |
Subtilisin BL
(Bacillus lentus) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article
| 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of Subtilisin BL wild type enzyme from B. lentus |
Bioorg Med Chem Lett 6: 2501-2506 (1996)
Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ |
More data for this Ligand-Target Pair | |
Subtilisin Carlsberg
(Bacillus licheniformis) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article
| 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentus |
Bioorg Med Chem Lett 6: 2501-2506 (1996)
Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ |
More data for this Ligand-Target Pair | |
Subtilisin BL
(Bacillus lentus) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article
| 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentus |
Bioorg Med Chem Lett 6: 2501-2506 (1996)
Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ |
More data for this Ligand-Target Pair | |
Subtilisin BL
(Bacillus lentus) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article
| 3.27E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentus |
Bioorg Med Chem Lett 6: 2501-2506 (1996)
Article DOI: 10.1016/0960-894X(96)00466-0 BindingDB Entry DOI: 10.7270/Q2X34XFJ |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Oxford
| Assay Description [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase... |
J Med Chem 51: 7057-60 (2008)
Article DOI: 10.1021/jm801051t BindingDB Entry DOI: 10.7270/Q25D8Q58 |
More data for this Ligand-Target Pair | |
Monoglyceride lipase
(Homo sapiens (Human)) | BDBM26126
((3-phenylphenyl)boranediol | Phenylboronic Acid, 5)Show InChI InChI=1S/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
| Assay Description The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ... |
J Med Chem 51: 7057-60 (2008)
Article DOI: 10.1021/jm801051t BindingDB Entry DOI: 10.7270/Q25D8Q58 |
More data for this Ligand-Target Pair | |