Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 371.4 BDBM50026524

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50026524 (2-Benzyl-7-phenyl-7-pyridin-3-yl-hept-6-enoic acid...) Show SMILES OC(=O)C(CCC\C=C(/c1ccccc1)c1cccnc1)Cc1ccccc1 Show InChI InChI=1S/C25H25NO2/c27-25(28)22(18-20-10-3-1-4-11-20)14-7-8-16-24(21-12-5-2-6-13-21)23-15-9-17-26-19-23/h1-6,9-13,15-17,19,22H,7-8,14,18H2,(H,27,28)/b24-16+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes				J Med Chem 28: 287-94 (1985) BindingDB Entry DOI: 10.7270/Q2P26ZPB
					More data for this Ligand-Target Pair