Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM345818
(US10202362, Compound T2.1)Show SMILES OC(=O)C1CCN(CC1)C(=O)CN1CCC(CC1)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 Show InChI InChI=1S/C28H32N4O5/c33-26(32-16-9-21(10-17-32)28(34)35)19-31-14-11-23(12-15-31)30-22-3-7-25(8-4-22)37-24-5-1-20(2-6-24)27-29-13-18-36-27/h1-8,13,18,21,23,30H,9-12,14-17,19H2,(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Celtaxsys, Inc.
US Patent
| Assay Description
LTB4 formed was quantified with the HTRF assay in which free LTB4 competes with LTB4-XL665 conjugate (acceptor) for anti-LTB4 monoclonal antibody lab... |
US Patent US10202362 (2019)
BindingDB Entry DOI: 10.7270/Q2MC9241 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM345818
(US10202362, Compound T2.1)Show SMILES OC(=O)C1CCN(CC1)C(=O)CN1CCC(CC1)Nc1ccc(Oc2ccc(cc2)-c2ncco2)cc1 Show InChI InChI=1S/C28H32N4O5/c33-26(32-16-9-21(10-17-32)28(34)35)19-31-14-11-23(12-15-31)30-22-3-7-25(8-4-22)37-24-5-1-20(2-6-24)27-29-13-18-36-27/h1-8,13,18,21,23,30H,9-12,14-17,19H2,(H,34,35) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Celtaxsys, Inc.
US Patent
| Assay Description
In brief, the enzyme (29 nM) was incubated with L-alanine-p-nitroanilide (1 mM) in 50 mM HEPES (pH 7.5), 100 mM KCL, 1% DMSO in the absence or presen... |
US Patent US10202362 (2019)
BindingDB Entry DOI: 10.7270/Q2MC9241 |
More data for this
Ligand-Target Pair | |