Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Thromboxane-A synthase
(Homo sapiens (Human)) | BDBM50036374
((Z)-6-[2-(4-Nitro-phenyl)-4-pyridin-3-yl-[1,3]diox...)Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22N2O6/c24-19(25)7-3-1-2-5-17-14-28-21(15-8-10-18(11-9-15)23(26)27)29-20(17)16-6-4-12-22-13-16/h1-2,4,6,8-13,17,20-21H,3,5,7,14H2,(H,24,25)/b2-1- | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro Inhibition of thromboxane synthase from human blood platelet microsomes |
J Med Chem 38: 686-94 (1995)
BindingDB Entry DOI: 10.7270/Q24Q7T2K |
More data for this Ligand-Target Pair | |
Prostacyclin synthase
(Homo sapiens (Human)) | BDBM50036374
((Z)-6-[2-(4-Nitro-phenyl)-4-pyridin-3-yl-[1,3]diox...)Show SMILES OC(=O)CC\C=C/CC1COC(OC1c1cccnc1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H22N2O6/c24-19(25)7-3-1-2-5-17-14-28-21(15-8-10-18(11-9-15)23(26)27)29-20(17)16-6-4-12-22-13-16/h1-2,4,6,8-13,17,20-21H,3,5,7,14H2,(H,24,25)/b2-1- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro inhibition of Prostaglandin I2 synthase from human blood platelet microsomes |
J Med Chem 38: 686-94 (1995)
BindingDB Entry DOI: 10.7270/Q24Q7T2K |
More data for this Ligand-Target Pair | |