Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 267.3 BDBM50026519

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50026519 (6-Phenyl-6-pyridin-3-yl-hex-5-enoic acid | CHEMBL1...) Show SMILES OC(=O)CCC\C=C(/c1ccccc1)c1cccnc1 Show InChI InChI=1S/C17H17NO2/c19-17(20)11-5-4-10-16(14-7-2-1-3-8-14)15-9-6-12-18-13-15/h1-3,6-10,12-13H,4-5,11H2,(H,19,20)/b16-10+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes				J Med Chem 28: 287-94 (1985) BindingDB Entry DOI: 10.7270/Q2P26ZPB
					More data for this Ligand-Target Pair