Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 299.3 BDBM50026495

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50026495 (7-(2-Fluoro-phenyl)-7-pyridin-3-yl-hept-6-enoic ac...) Show SMILES OC(=O)CCCC\C=C(/c1cccnc1)c1ccccc1F Show InChI InChI=1S/C18H18FNO2/c19-17-10-5-4-9-16(17)15(14-7-6-12-20-13-14)8-2-1-3-11-18(21)22/h4-10,12-13H,1-3,11H2,(H,21,22)/b15-8+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes				J Med Chem 28: 287-94 (1985) BindingDB Entry DOI: 10.7270/Q2P26ZPB
					More data for this Ligand-Target Pair