Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 323.4 BDBM50026485

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50026485 (10-Phenyl-7-pyridin-3-yl-dec-6-enoic acid | CHEMBL...) Show SMILES OC(=O)CCCC\C=C(\CCCc1ccccc1)c1cccnc1 Show InChI InChI=1S/C21H25NO2/c23-21(24)15-6-2-5-12-19(20-14-8-16-22-17-20)13-7-11-18-9-3-1-4-10-18/h1,3-4,8-10,12,14,16-17H,2,5-7,11,13,15H2,(H,23,24)/b19-12-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against thromboxane B2 formation (TXA2 synthase) by incubating prostaglandin H2 (PGH-2) with horse platelet microsomes				J Med Chem 28: 287-94 (1985) BindingDB Entry DOI: 10.7270/Q2P26ZPB
					More data for this Ligand-Target Pair