Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Thromboxane-A synthase
(Homo sapiens (Human)) | BDBM50071129
((Z)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)Show SMILES OC(=O)CCCC\C=C(\c1ccc(cc1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1)c1cccnc1 |t:16| Show InChI InChI=1S/C32H41N3O4/c36-30(37)15-6-2-5-14-28(27-13-9-20-33-22-27)25-16-18-26(19-17-25)32-35-29(23-39-32)31(38)34-21-8-7-12-24-10-3-1-4-11-24/h9,13-14,16-20,22,24,29H,1-8,10-12,15,21,23H2,(H,34,38)(H,36,37)/b28-14-/t29-/m1/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of thromboxane synthase (TSI) activity was determined by using human serum levels of TXB2 |
Bioorg Med Chem Lett 8: 1943-8 (1999)
BindingDB Entry DOI: 10.7270/Q2DB8107 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50071129
((Z)-7-{4-[(R)-4-(4-Cyclohexyl-butylcarbamoyl)-4,5-...)Show SMILES OC(=O)CCCC\C=C(\c1ccc(cc1)C1=N[C@H](CO1)C(=O)NCCCCC1CCCCC1)c1cccnc1 |t:16| Show InChI InChI=1S/C32H41N3O4/c36-30(37)15-6-2-5-14-28(27-13-9-20-33-22-27)25-16-18-26(19-17-25)32-35-29(23-39-32)31(38)34-21-8-7-12-24-10-3-1-4-11-24/h9,13-14,16-20,22,24,29H,1-8,10-12,15,21,23H2,(H,34,38)(H,36,37)/b28-14-/t29-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro thromboxane receptor antagonism was determined using a human platelet binding assay |
Bioorg Med Chem Lett 8: 1943-8 (1999)
BindingDB Entry DOI: 10.7270/Q2DB8107 |
More data for this
Ligand-Target Pair | |