Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Thromboxane-A synthase
(Rattus norvegicus) | BDBM50037727
(6-[2-Imidazol-1-yl-1-phenyl-eth-(Z)-ylideneaminoox...)Show InChI InChI=1S/C17H21N3O3/c21-17(22)9-5-2-6-12-23-19-16(13-20-11-10-18-14-20)15-7-3-1-4-8-15/h1,3-4,7-8,10-11,14H,2,5-6,9,12-13H2,(H,21,22)/b19-16+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba
Curated by ChEMBL
| Assay Description In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade |
J Med Chem 37: 3588-604 (1994)
BindingDB Entry DOI: 10.7270/Q2C24VFD |
More data for this Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50037727
(6-[2-Imidazol-1-yl-1-phenyl-eth-(Z)-ylideneaminoox...)Show InChI InChI=1S/C17H21N3O3/c21-17(22)9-5-2-6-12-23-19-16(13-20-11-10-18-14-20)15-7-3-1-4-8-15/h1,3-4,7-8,10-11,14H,2,5-6,9,12-13H2,(H,21,22)/b19-16+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba
Curated by ChEMBL
| Assay Description In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets |
J Med Chem 37: 3588-604 (1994)
BindingDB Entry DOI: 10.7270/Q2C24VFD |
More data for this Ligand-Target Pair | |