Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Thromboxane-A synthase
(Homo sapiens (Human)) | BDBM50053753
(5-[1-Phenyl-1-pyridazin-3-yl-meth-(E)-ylideneamino...)Show InChI InChI=1S/C16H17N3O3/c20-15(21)10-4-5-12-22-19-16(13-7-2-1-3-8-13)14-9-6-11-17-18-14/h1-3,6-9,11H,4-5,10,12H2,(H,20,21)/b19-16+ | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by ChEMBL
| Assay Description TXA2 synthetase inhibition measured by the inhibition of TXB2 formation by human gel-filtered platelets incubated with [14C]-arachidonic acid |
J Med Chem 39: 4058-64 (1996)
Article DOI: 10.1021/jm960341g BindingDB Entry DOI: 10.7270/Q2ZP456G |
More data for this Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50053753
(5-[1-Phenyl-1-pyridazin-3-yl-meth-(E)-ylideneamino...)Show InChI InChI=1S/C16H17N3O3/c20-15(21)10-4-5-12-22-19-16(13-7-2-1-3-8-13)14-9-6-11-17-18-14/h1-3,6-9,11H,4-5,10,12H2,(H,20,21)/b19-16+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by ChEMBL
| Assay Description TXA2 receptor antagonism, measured by the displacement of [3H]SQ29,548 from the PGH-2/TXA-2 receptor on human platelets |
J Med Chem 39: 4058-64 (1996)
Article DOI: 10.1021/jm960341g BindingDB Entry DOI: 10.7270/Q2ZP456G |
More data for this Ligand-Target Pair | |