Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116540
(3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...)Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University (GNU)
Curated by ChEMBL
| Assay Description Inhibition of human leukotriene A4 hydrolase |
Eur J Med Chem 46: 1593-603 (2011)
Article DOI: 10.1016/j.ejmech.2011.02.007 BindingDB Entry DOI: 10.7270/Q2K64JDG |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116540
(3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...)Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human leukotriene A4 hydrolase (LTA-4). |
J Med Chem 45: 3482-90 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1KMF |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50116540
(3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...)Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human whole blood LTB-4 production (Leukotriene B-4). |
J Med Chem 45: 3482-90 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1KMF |
More data for this Ligand-Target Pair | |